Catherine Dulac
Catherine Dulac is a biologist notable for research on the molecular biology of olfactory signaling in mammals, particularly including pheromones.[1] She developed a novel screening strategy based on screening cDNA libraries from single neurons and a new method of cloning genes from single neurons. As a postdoc, Dulac discovered the first family of mammalian pheromone receptors with Nobel laureate Richard Axel. Dulac is an Howard Hughes Medical Investigator at Harvard University's Department of Molecular and Cellular Biology.
Biography
Dulac grew up in Montpellier, France, and graduated from the École Normale Supérieure de la rue d'Ulm, Paris, and earned a Ph.D. in developmental biology from the University of Paris in 1992. She worked with Nicole Le Douarin on developmental mechanisms, and did a postdoc with Richard Axel at Columbia University where she identified the first genes encoding mammalian pheromone receptors.
Dulac joined the faculty of Harvard in 1996,[2] and was promoted to associate professor in 2000 and full professor in 2001. She is currently an investigator at the Howard Hughes Medical Institute.
Publications
Notable papers
- Kimchi T., Xu, J., and Dulac, C. "A Functional Circuit Underlying Male Sexual Behaviour in the Female Mouse Brain," Nature, v.448, pp. 1009–1014 (2007).
- Tietjen I, Rihel JM, Cao Y, Koentges G, Zakhary L, Dulac C. "Single-cell transcriptional analysis of neuronal progenitors.", Neuron, v.38, pp. 161–75 (2003).
- Pantages, E., and Dulac, C. "A New Family of Candidate Pheromone Receptors in Mammals," Neuron, v.28, pp. 835–845 (2000).
- Liman, E., Corey, D., and Dulac, C. "TRP2: A Candidate Transduction Channel for Mammalian Pheromone Sensory Signaling", PNAS, v.96, pp. 5791–5796 (1999).
- Belluscio, L., Koentges, G., Axel, R., and Dulac, C., "A Map of Pheromone Receptor Activation in the Mammalian Brain," Cell, v.97, pp. 209–220 (1999).
- Dulac C. and Axel R., "A Novel Family of Genes Encoding Putative Pheromone Receptors in Mammals," Cell, v.83, pp. 195–206 (1995).
Other
- Dulac, C. "Sex and the Single Splice," Cell, v.121, pp. 664–666 (2005).
- Dulac, C. and Grothe, B. "Editorial: Sensory Systems." Current Opinion in Neurobiology, v.14, pp. 403–406 (2004).
- Dulac, C. and Torello, A.T., Review, "Molecular Detection of Pheromone Signals in Mammals: From Genes to Behaviour." Nature Reviews Neuroscience, v. 4, pp. 1–13 (2003)
- Dulac, C. "The Physiology of Taste, Vintage 2000", Cell, v.100, pp. 607–610 (2000).
Awards & Honors
Further reading & External links
Notes
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